gemcitabine IV

Nausea, vomiting, diarrhea, pain/redness at the injection site, and flu-like symptoms (e.g., fever, muscle aches) may occur. Nausea and vomiting can be severe. In some cases, drug therapy may be needed to prevent or relieve nausea and vomiting. Changes in diet and lifestyle, such as eating several small meals or limiting activity, may help lessen some of these effects. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Temporary hair loss may occur. Normal hair growth should return after treatment has ended.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: dizziness, fainting, mouth sores, numbness/tingling of hands/feet, swelling of ankles/feet, severe stomach/abdominal pain, easy bleeding/bruising, cough, difficulty catching your breath (shortness of breath, wheezing), unusual tiredness, fast/irregular heartbeat, change in amount of urine, dark urine, yellowing of the eyes/skin.
Get medical help right away if any of these rare but very serious side effects occur: chest pain, jaw/left arm pain, weakness on one side of the body, slurred speech, vision changes, confusion.
This medication can lower your ability to fight an infection (bone marrow depression). Notify your doctor promptly if you develop any signs of infection (e.g., high fever, chills, persistent sore throat).
An allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using gemcitabine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: bone marrow problems (e.g., leukopenia, thrombocytopenia, anemia), heart problems (e.g., irregular heartbeat, heart failure), kidney problems, liver problems, radiation therapy.
Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine.
Wash your hands well to prevent the spread of infections.
To lower the chance of getting cut, bruised or injured, use caution with sharp objects like safety razors or nail cutters, and avoid activities such as contact sports. Use a soft-bristle toothbrush to lessen the risk of bleeding gums.
This medication is not recommended for use during pregnancy. Consult your doctor for more details and to discuss reliable forms of birth control. It is recommended that men and women use two effective forms of birth control (e.g., condoms and birth control pills) while taking this medication and for some time afterwards.
It is not known whether this medication passes into breast milk. Because of the potential harm to the nursing infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor\'s approval.

If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

NOTES:
Laboratory and/or medical tests (e.g., complete blood counts before each dose, kidney function tests, liver function tests) should be performed from time to time to monitor for side effects and response to treatment. Consult your doctor for more details. Keep all scheduled medical appointments.

MISSED DOSE:
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.

STORAGE:
Not applicable. This medication is given in a clinic and will not be stored at home.
MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).
Information last revised September 2010. Copyright(c) 2010 First Databank, Inc.