Naphazoline is a decongestant used to relieve redness, puffiness, and itchy/watering eyes due to colds, allergies, or eye irritations (smog, swimming, or wearing contact lenses). It is known as a sympathomimetic (alpha receptor agonist) that works in the eye to decrease congestion.
Some brands of naphazoline eye drops also contain other ingredients. Lubricants (such as glycerin, hypromellose, or polyethylene glycol 300) help protect the eyes from more irritation. Zinc sulfate, an astringent, helps reduce redness and irritation.

How to use Estivin II Opht
Follow all directions on the product package, or use as directed by your doctor. If you are uncertain about any of the information, consult your doctor or pharmacist.
To apply eye drops, wash your hands first. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface.
Remove contact lenses before applying the eye drops. Wait at least 10 minutes after using this medication before inserting contact lenses.
Before using, check this product visually. Do not use if the liquid has changed color or is cloudy. Use in affected eye(s) as directed.
Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over the eye and place 1 drop into the pouch. Look downward and gently close your eyes for 1 to 2 minutes. Place one finger at the corner of the eye near the nose and apply gentle pressure. This will prevent the medication from draining away from the eye. Try not to blink and do not rub the eye. Repeat these steps if your dose is for more than 1 drop and for the other eye if so directed.
Do not rinse the dropper. Replace the dropper cap tightly after each use.
If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying other medications. Use eye drops before eye ointments to allow the eye drops to enter the eye.
Overuse of this type of medication may result in increased eye redness (rebound hyperemia). Tell your doctor if this occurs or if your condition persists or worsens after 48 hours. If you develop eye pain/vision changes or think you may have a serious medical problem, seek immediate medical attention

Stinging, redness, widened pupils, or blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: dizziness, nausea, sweating, drowsiness, weakness, nervousness, worsening redness/itching/swelling in or around the eyes.
Tell your doctor immediately if any of these rare but very serious side effects occur: eye pain, other vision problems, headache, decrease in body temperature, irregular heartbeat.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Before using naphazoline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., high blood pressure), glaucoma, diabetes, eye infection/injury, overactive thyroid (hyperthyroidism).
After you apply this drug, your vision may become temporarily blurred. This drug may also make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.
Caution is advised when using this drug in children because they may be more sensitive to its effects, especially severe drowsiness and severely decreased body temperature.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor\'s approval.
Some products that may interact with this drug include: cyclobenzaprine, guanethidine, MAO inhibitors (linezolid, methylene blue, moclobemide, phenelzine procarbazine, rasagiline, selegiline, isocarboxazid, tranylcypromine), maprotiline, tricyclic antidepressants (e.g., amitriptyline).

This medicine may be harmful if swallowed. If swallowing or overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

NOTES:
If your symptoms are due to allergies, avoid allergens that may be the cause of your symptoms. Some common causes of allergies include pollen, grasses, weeds, dust mites, and pet dander.
Keep all regular medical and laboratory appointments.
If this medication has been prescribed for you, use it for your current condition only. Do not use it later for another condition unless directed to do so by your doctor. A different medication may be necessary in that case.

MISSED DOSE:
If your doctor has directed you to use this medication on a regular schedule and you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE:
Store dropper bottle upright at room temperature between 68-77 degrees F (20-25 degrees C) away from moisture and sunlight. Do not store in the bathroom. Discard if drops become discolored or cloudy. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
Information last revised September 2011. Copyright(c) 2011 First Databank, Inc.